Der Artikel ist weiterhin als ^^OTHERCONDITION^^ verfügbar.
Autor: Marc Galanter
ISBN-13: 9780306415340
Einband: Buch
Seiten: 444
Gewicht: 960 g
Sprache: Englisch
Erscheinungsdatum: 01.02.1984
I. Experimental Social and Learning Models of Drinking.- Overview.- 1 A Conditioning Model of Alcohol Tolerance.- 1. Introduction.- 2. Learning and Tolerance.- 2.1. Practice.- 2.2. Pavlovian Conditioning.- 3. Mechanisms.- 3.1. Neurochemistry.- 3.2. Dispositional Tolerance.- 4. Influence on Drinking and Treatment Implications.- 5. Conclusions.- References.- 2 Social Models of Drinking Behavior in Animals: The Importance of Individual Differences.- 1. Animal Models in Medicine and Psychiatry.- 1.1. Neurological Models and Alcohol.- 1.2. Voluntary Alcohol Consumption in Animals.- 2. Effects of Socialization on Alcohol Consumption in Humans and Animals.- 2.1. Social Housing and Alcohol Consumption in Animals.- 2.2. Social Imitation and Alcohol Consumption in Animals.- 2.3. Alcohol Consumption, Dominance Standing, and Social Tension.- 3. Effects of Alcohol Administration on Social Behaviors.- 3.1. Low Doses of Alcohol Increase Aggressive Behaviors.- 3.2. Effects of Acute Alcohol on Other Social Behaviors.- 3.3. Effects of Chronic Alcohol on Social Behaviors.- 3.4. Fetal Alcohol and Maternal Behaviors.- 4. A New Animal Model of Alcoholism Based on Individual Differences That Develop in Social Colonies.- 4.1. Colony-Raised Animals Develop Extremes of Alcohol Preference Compared to Caged Isolates.- 4.2. Behavioral Correlates of the High-Alcohol Consumer.- 4.3. Implications of These Findings: A New Animal Model of Alcoholism.- References.- 3 Social Correlates of Drinking in Contrived Situations.- 1. Introduction.- 2. Drinking Behavior in Natural and Contrived Settings.- 3. Solitary vs. Social Drinking.- 4. Social Drinking and Fantasy.- 5. Drinking and Aggression.- 6. Alcohol and Social Integration in Patients with Psychiatric Syndromes.- 7. Contrived Drinking Situations with Alcoholics.- 8. Social Organization and Affiliation during Alcohol Intoxication.- 9. Issues for Future Research.- References.- 4 Alcohol-Ingestive Habits: The Role of Flavor and Effect.- 1. Principles of Oral Ingestive Habits.- 1.1. Alcohol Consumption as a Feeding Habit.- 1.2. Flavor and Effect as Conditioning Stimuli.- 1.3. Seven Distinctive Features of Flavor-Effect Conditioning.- 1.4. Neural Mechanisms of Flavor and Effect.- 2. Flavor and Effect of Alcohol.- 2.1. Flavor of Alcohol as a Conditioned Stimulus.- 2.2. Effect of Alcohol as an Unconditioned Stimulus.- 3. Interactions between the Feeding System and Other Functional Systems.- 3.1. Antagonistic Processing of Odor: Feeding vs. Defense.- 3.2. Increased Drinking Associated with Fear, Pain, and Stress.- 4. Summary: Implications for Modifying Alcoholic Habits.- References.- 5 Commentary on the Utility of Experimental Social and Learning Models of Alcoholism.- 1. Introduction.- 2. Status of Scientific Models.- 3. What Do Animal Models of Alcoholism Model?.- 4. Models of Alcohol Phenomena.- 4.1. Conditioned Tolerance.- 4.2. Conditioned Aversion and Preference.- 4.3. Social Models of Drinking Behavior in Animals.- 4.4. Social Correlates of Human Alcohol Drinking.- 5. Summary and Conclusions.- References.- II. Alcohol and the Liver: Recent Developments in Preclinical and Clinical Research.- Overview.- 6 Alcohol-Induced Liver Injury: The Role of Oxygen.- 1. Introduction.- 2. NADH Fluorescence from Pericentral and Periportal Regions of the Liver Lobule.- 3. Oxygen Gradient Measured with Mini-Oxygen Electrode.- 4. Local Rates of Ethanol and Acetaldehyde Uptake.- 5. Centrilobular Damage Due to Low-Flow Hypoxia.- 6. Clinical Implications.- References.- 7 Hypermetabolic State and Hypoxic Liver Damage.- 1. Introduction.- 2. Validity of the Premise.- 3. Hypermetabolic State.- 3.1. Relationship between An Increased Rate of Oxygen Consumption by the Liver and Metabolic Tolerance.- 3.2. Permissive Role of Thyroid Hormones.- 3.3. Role of the (Na+-K+)-Adenosine Triphosphatase in the Hypermetabolic State.- 3.4. Centrilobular Hypoxia in Relation to a Hypermetabolic State following Chronic Alcohol Consumption.- References.-
From the President of the Research Society on Alcoholism The field of alcohol research has been slowly but continuously evolving, taking into its domain an ever-increasing array of scientific disciplines. This senes is designed to fill the need for ,a review publication that covers the broad range of research into alcohol actions and alcoholism. Research in alcohol concerns social, epidemiological, and legal concerns in addition to biomedical and behavioral topics to greater degree than research with many other drugs. A publication devoted to alcohol research should serve the broadest existing research community, but perhaps more important, it should also provide a means to recruit new investigators with fresh approaches to the field. We can and must demonstrate that legitimate, high-quality research is being done, but we must also highlight the opportunity for new workers to make a real impact on the problem. The Research Society on Alcoholism seeks to provide such a service not only through this publication but also through other ac tivities. Richard A. Deitrich, Ph.D.
Autor: Marc Galanter
ISBN-13:: 9780306415340
ISBN: 0306415348
Erscheinungsjahr: 01.02.1984
Verlag: Springer, Berlin
Gewicht: 960g
Seiten: 444
Sprache: Englisch
Sonstiges: Buch, 17 SW-Abb.